Endocrinology of the heart

In the heart of mammals, atrial cardiocytes produce in a regulated manner the polypeptide hormones like brain natriuretic peptide and atrial natriuretic factor.The biological actions of BNP and ANF are similar and they include the modulation of systems that will lead to increase extracellular fluid volume and blood pressure, such as the sympathetic nervous system and the renin–angiotensin system.